Noopept

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Russian noopept

Noopept is a Russian dipeptide nootropic drug. It is one of the most popular nootropics around the world.

It is suggested that Noopept works as a prodrug to cycloprolylglycine. Cycloprolylglycine is an endogenous neuropeptide with anxiolytic and neurotrophic properties and is shown to be a positive allosteric AMPA receptors modulator. The pharmacological effects and uses of Noopept are mostly the same as Piracetam, a reference nootropic drug.

Noopept is used to improve cognitive functions (especially memory) in both healthy and cognitively impaired individuals, and in the therapy of organic brain syndrome.

Indications for use are:

  • Traumatic brain injuries
  • Post-concussion syndrome
  • Cerebrovascular disorders
  • Asthenic conditions (aka chronic fatigue)
  • Decreased mental capacity

Noopept does have cumulative action, thus it is advised to take it for at least couple weeks to experience therapeutic effects. A choline-rich diet or additional supplementation with Choline is recommended while taking Noopept.

Dosage and administration

The recommended dosage is 10mg twice daily after a meal. If necessary, the dosage can be raised to 10mg three times a day. It is not recommended to take Noopept before bed to avoid sleep disturbances. The length of the treatment course is 1.5-3 months. The course can be repeated in 1 month if necessary.

Side effects

  • Allergic reactions
  • Hypertension

Contraindications

  • Hypersensitivity
  • Pregnancy and lactation
  • Lactose intolerance
  • Liver and renal insufficiency