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Tenoten is a novel homeopathic anxiolytic with mild nootropic and antidepressant activity. The active ingredient is antibodies to brain-specific protein S100 that is expressed and secreted by astrocytes and microglial cells. 

The studies of the impact of S100 protein and its antibodies on the nervous system began in the 1960’s. During these researches, it was found that the low dosages of S100 antibodies can be used for the treatment of certain dependencies.

It acts as anxiolytic by interacting with GABA-A receptors and the opening of a chloride ion-selective channels. The drug modulates synaptic plasticity and increases brain resistance to hypoxia. It also improves cerebral blood flow, thus having some impact on cognition. 

Recommended dosage is 1-2 pills sublingually 2-4 times a day. The length of the course is from one to three months. The treatment course can be repeated after 1-2 months.